Spot is a software package for the analysis of microarray images.
cDNA microarrays, or 'DNA chips', are used to analyse the
expression levels of large collections of genes. Spot is a
microarray spot detection and characterisation package which
extracts more meaningful numerical information than other
For example, Spot can accommodate non-circularity of spots and
employs superior between-the-spots (background) estimation
techniques. Appropriate background adjustment can substantially
improve the precision of low-intensity spot values. An automatic
grid-finding procedure also minimises manual intervention.
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